Page 3 - Carnot

Know-how and skills

Pheno-genotyping: natural history, phenotypic KEY FIGURES
and genomic characterisation of patients,
phenotype/genotype correlation, cohort studies 164
and stratifications, bioinformatics, single cell
RNAseq analysis, identification of new relevant Permanent staff
therapeutic targets. (full-time equivalent)

Preclinical research: creation of cellular 92
and animal models (iPSC, CRISPR-Cas9),
characterisation of cellular and molecular PhD students
mechanisms, cell and gene therapies,
establishment of preclinical and clinical proof of 2 242 K€
concepts. Partnership incomes
Clinical research: setting up clinical projects with industry
(including clinical trials and orphan drug
designations), interaction with regulatory 324 K€
authorities, operational and logistical support Collaborative research
during studies, decision support (databases,
clinical expertise) to identify targeted patient 1 918 K€
recruitment.
Services

Partnerships are at the heart of

our strategy Objectives

Research collaborations and services, creation Improve our knowledge to better target the
and support of start-ups, on preclinical, pathophysiological mechanisms of rare genetic
translational or clinical projects. diseases
Molecule discovery, repositioning, gene and Accelerate the transformation of know-how into
cell therapy in partnership with small and large therapeutic and diagnostic solutions for the benefit
pharmaceutical, biotechnology and diagnostic of the patient as quickly as possible
companies.
Increase the number of innovative therapeutic
Institut Carnot Imagine’s offer is available on: studies (gene and cell therapies) and the number
https://techtransfer.institutimagine.org of patients participating in these studies